Complete genetic analysis of thrombophilia

Home Complete genetic analysis of thrombophilia

Cardiovascular Diseases (CVC) are common but in many cases can be avoided. Atherosclerosis and venous thrombosis are two major manifestations of CVD, both caused by complex interactions of environmental and genetic parameters. Testing for genetic variations and adequate prophylaxis contribute to lower CVD risks.

Our laboratory provides a combined detection of 12 mutations/polymorphisms associated with the genetically determined risk of thrombophilia.

Method

In order to detect the following 12 mutations/polymorphisms (FV G1691A (Leiden), FV H1299R (R2), PTH G20210A, Factor XIII V34L, β-Fibrinogen -455 GA, PAI -1 4G/5G, GPIIIa L33P (HPA-1), MTHFR C677T, MTHFR A1298C, ACE I/D, ApoB R3500Q and Apo E2/E3/E4), a multiplex PCR reaction using the appropriate biotinylated primers in combination with reverse hybridization are performed.

Sample type: Peripheral blood in EDTA

Time to result: 2 weeks